Scientists at City of Hope and the Broad Institute and Keio University have discovered how specific gut bacteria work ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study led by ...

When myelin breaks down, white matter in the brain deteriorates, a change commonly seen with aging. At the same time, microglia, the brain’s primary immune cells, can shift from protective responders ...

After treatment, the mice’s memories were essentially shunted back into a younger state. The researchers found that reprogrammed engrams displayed molecular behavior of more youthful cells. Using a ...

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Distinct outcomes with the detection of endemic Burkitt lymphoma, T-cell receptor (TCR) complementarity determining region-3s (CDR3s) matching known anti-HIV TCR CDR3s. This is an ASCO Meeting ...