Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

A Japanese research team has demonstrated that the use of antisense oligonucleotides (ASOs) with modified bases and sugars can enhance the effectiveness of targeting diseases in the central nervous ...

A study by Oregon Health & Science University researchers has uncovered a new way proteins can be changed inside cells. This discovery could be important for understanding how the immune system works.

In recent decades, significant advances in science and technology have greatly enhanced understanding of the many biological molecules that contribute to life’s complexity. RNA is one such molecule ...

Diseases that affect the brain and spinal cord can be particularly devastating, and finding new and more effective ways to treat these conditions is an important goal for researchers and clinicians ...

To understand more fully the role of RNA and its modifications in living systems, researchers will need robust, reproducible, and accessible tools and techniques capable of identifying all RNA ...