Circular single-stranded DNA viruses represent a diverse group of pathogens that possess a covalently closed, circular single-stranded DNA genome. Their small genomes belie a sophisticated replication ...

A new family of enzymes enables precise cuts in single-stranded DNA, offering powerful new tools for genetic engineering and expanding possibilities in biotechnology. (Nanowerk News) A few years ago, ...

An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...

A new single-molecule flow-stretch assay enables real-time observation of DNA-protein interactions to identify the molecular ...

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting ...

Figure 1. Design and synthesis of circAMO . (a) Synthesis of a single-molecule ring by rigid regulation of selectivity; (b) Schematic diagram of circAMO design; (c) Synthesis of circAMO; (d) ...

The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...

Single-walled carbon nanotubes (SWCNTs) hold promise for biomedicine and nanoelectronics, yet the functionalization with single-stranded DNA (ssDNA) remains a challenge. Researchers using ...