Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...
Spatial proteomics is a spatial biology method that helps study the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular ...
In this GEN Learning Lab, our expert panelists Linda Orzolek, MS, MB, Xuhuai Ji, MD, PhD, and Christina Chang, PhD, will discuss the current landscape of imaging- and next-generation sequencing-based ...
Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...
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3D spatial mapping of tumor cell 'neighborhoods' reveals potential targets for personalized cancer therapy
Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...
The spatial distribution of cell surface proteins, which governs vital processes of the immune system such as inter-cell communication and mobility, has proven difficult to assess. New tools are ...
Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to ...
In a recent study posted to the medRxiv* preprint server, researchers used in situ sequencing and spatial single-cell transcriptome analysis (SSCTA) to examine postmortem coronavirus disease 2019 ...
MSK immunologist Dr. Andrea Schietinger and colleagues found that a 'triad' of immune cells is required to kill cancer cells. The discovery could alter the way doctors administer immunotherapies.
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