Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Touch—the first sense to develop in the womb—is fundamental to our bodily experience and our everyday lives. Yet, as the least studied of the five senses, it remains somewhat mysterious at the ...

A team led by HHMI Hanna Gray Fellow Shan Meltzer has created a detailed, cell-by-cell map of the spinal cord that offers a new framework for understanding chronic pain and provides a powerful new ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

The collaborations will provide Illumina's customers with workflows for genomic disease characterization and spatial mapping.

Researchers from the National University of Singapore (NUS) have developed CellScope, a high-performance single-cell analysis ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...

Illustration of a spatial imprint of captured transcripts by Nova-ST, along with the localization of binned clustering, for a coronal section of the mouse brain. The illustration below the brain ...