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New NIH-funded brain tumor research led by @UCSF neurosurgery resident Alex Haddad, MD, and neurosurgeon Manish Aghi, MD, PhD, developed a novel viral immunotherapy for glioblastoma. The innovative approach uses a replicating retrovirus to turn the tumor cells into biofactories that produce an immune-stimulating cytokine called receptor-linked IL-15, generating a durable anti-tumor response. Read the full study at the link in our bio. #ScienceTok #glioblastoma #immunotherapy
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For the first time, an AI model designed viruses that had never existed in nature (and they worked) 🧬 Scientists used an AI model called Evo, trained on 9 trillion nucleotides across the tree of life, to design viruses that never existed in nature. 🦠 Of ~700,000 generated genomes, they built 300 and 16 came to life, infecting and killing bacterial cells. ⚡ A few AI-designed versions actually spread faster than the natural Phi X 174 💊 The upside is phage therapy against drug-resistant infectio
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